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Exploratory Clinical Neuroscience Research on Substance Use Disorders

Agency: National Institutes of Health

Assistance Listings: 93.279 -- Drug Use and Addiction Research Programs

Last Updated: March 16, 2026

Description

This Notice of Funding Opportunity (NOFO) uses a R61/R33 Phased Innovation Award mechanism to support clinical research applications that are exploratory and developmental in nature and focus on understanding the neurobiological mechanisms underlying SUD, including fundamental brain function relevant to substance use. This NOFO is particularly designed to support exploratory/developmental projects requiring budgets that would exceed that allowed for the R21 mechanism (Neuroscience Research on Drug Abuse (R21 Clinical Trial Optional)

Eligibility

Eligible applicants

Government

  • State governments
  • Public and Indian housing authorities
  • City or township governments
  • Federally recognized Native American tribal governments
  • County governments
  • Special district governments

Nonprofit

  • Other Native American tribal organizations
  • Nonprofits non-higher education without 501(c)(3)
  • Nonprofits non-higher education with 501(c)(3)

Business

  • Small businesses
  • For-profit organizations other than small businesses

Miscellaneous

  • Other

Education

  • Public and state institutions of higher education
  • Private institutions of higher education
  • Independent school districts

Additional information

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Grantor contact information

Description

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Email

NIDA_DNB_BCNB_r61@nih.gov

NIDA_DNB_BCNB_r61@nih.gov

Documents

No documents are currently available.

Link to additional information

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Forecasted

Estimated Post Date:

June 1, 2026

Estimated Application Due Date:

July 10, 2026

Estimated Due Date Description:

Not available

Estimated Award Date:

April 1, 2027

Estimated Project Start Date:

April 1, 2027

Fiscal Year:

2026

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$--

Program Funding

6

Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

PAR-26-093

Cost sharing or matching requirement:

No

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

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Category of Funding Activity:

Health

Category Explanation:

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History

Version:

1

Forecast posted date:

March 16, 2026

Archive date:

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