Assessing the Effectiveness of Programs, Policies, or Practices that Affect Social Determinants of Health to Promote Health Equity and Reduce Health Disparities in Chronic Diseases

The purpose of this NOFO is to support rapid, applied research with rigorous study design (i.e., natural experiments, quasi-experimental design studies, simulation modeling, and economic evaluations) to evaluate the impact of ongoing programs, policies, and environmental improvement strategies on SDOH and how these changes in SDOH improve chronic disease outcomes and related health disparities. The funded sites are expected to work together to create a network. This NOFO has three (3) components to achieve the purpose of the program: Component A (Research Studies to Assess Inequities in Addressing...

For an application to be considered, the application must be responsive to these Special Eligibility Requirements. If your application is incomplete or non-responsive to the special eligibility requirements listed in this section, it will not enter into the review process. Component A: Research Studies to Assess the Impact of Programs, Policies, or Practices that Address SDOH on Chronic Disease-Related Health Disparities 1. Applicants must have continuous access to data sets and/or data systems needed to accomplish study objectives and a minimum study sample size of 10,000 individuals for each priority area selected. 2. Applicants must have approval for unrestricted publication of the study findings, regardless of study outcomes. 3. Applicants may not request funding above the ceiling amount (direct and indirect) listed below: Tier 1: $600,000 Tier 2: $700,000 Tier 3: $800,000 Tier 4: $900,000 Tier 5: $1,000,000 Component B: SDOH Simulation Model Development Applicants must have access to the clinical and real-world data that are needed to develop and validate the simulation model.  Applicants may not request funding above the ceiling amount of $1,000,000 (direct and indirect). Component C: Coordinating Center 1. Applicants for Component C must apply for Component A or Component B. 2. Applicants may not request funding above the ceiling amount of $500,000 (direct and indirect).

Sue Shaw zgx7@cdc.gov