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Pilot and Feasibility Studies in Preparation for Substance Use and HIV Prevention Intervention and Services Research Trials

Agency: National Institutes of Health

Assistance Listings: 93.279 -- Drug Use and Addiction Research Programs

Last Updated: January 26, 2026

Description

The National Institute on Drug Abuse seeks to support pilot and feasibility studies in preparation for efficacy, effectiveness and/or services research trials. Topics may include:1) developing interventions to prevent substance use, misuse or progression to disorder, 2) substance use prevention, treatment or recovery services research, including comorbid pain, medical and mental health disorders, 3) HIV eradication research, including implementation science, prevention, treatment and recovery in substance use settings/populations.

Projects may address information gaps, strengthen stakeholder partnerships, or pilot test interventions. Activities might include intervention development/adaptation; assessing intervention or service model acceptability and feasibility; and development of measures, materials, or methods for the future trial. Preliminary data is not required. A well-defined theory of change or logic model is expected. Applicants must engage relevant end users in study design, execution, and interpretation (e.g., policymakers, state and local decision makers, practitioners, individuals with lived/living experience, families, youth, and community members).

Applications are not being solicited at this time. This notice is to allow applicants time to develop collaborations and responsive projects. Grant authorities that allow this forecast are 42 U.S.C. §§ 241 and 284.

 

Eligibility

Eligible applicants

Government

  • State governments
  • City or township governments
  • County governments
  • Federally recognized Native American tribal governments
  • Special district governments
  • Public and Indian housing authorities

Miscellaneous

  • Other

Education

  • Public and state institutions of higher education
  • Private institutions of higher education
  • Independent school districts

Nonprofit

  • Nonprofits non-higher education without 501(c)(3)
  • Nonprofits non-higher education with 501(c)(3)
  • Other Native American tribal organizations

Business

  • For-profit organizations other than small businesses
  • Small businesses

Additional information

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Grantor contact information

Description

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Email

Division of Epidemiology Services and Prevention Research

nida-par-26-092@mail.nih.gov

Documents

No documents are currently available.

Link to additional information

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Forecasted

Estimated Post Date:

July 2, 2026

Estimated Application Due Date:

October 2, 2026

Estimated Due Date Description:

Not available

Estimated Award Date:

July 1, 2027

Estimated Project Start Date:

July 1, 2027

Fiscal Year:

2027

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$--

Program Funding

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Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

PAR-26-092

Cost sharing or matching requirement:

No

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

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Category of Funding Activity:

Health

Category Explanation:

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History

Version:

1

Forecast posted date:

January 26, 2026

Archive date:

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