Pilot and Feasibility Studies in Preparation for Substance Use and HIV Prevention Intervention and Services Research Trials (R34 Clinical Trial Optional)
Agency: National Institutes of Health
- 93.310 -- Trans-NIH Research Support
- 93.681 -- Office of Disease Prevention
- 93.279 -- Drug Use and Addiction Research Programs
Open opportunityLast Updated: Oct 19, 2026
View version history on Grants.gov
Description
The purpose of this notice of funding opportunity (NOFO) is to support pilot and feasibility studies to inform the design and conduct of efficacy, effectiveness, and/or services research trials. Topics may include: 1) developing interventions to prevent substance use, misuse, or progression to substance use disorder; 2) prevention, treatment, or recovery services research, including research addressing comorbid pain and medical and mental health disorders; and 3) HIV eradication research, including implementation science, prevention, treatment and recovery in substance use settings/populations.
Eligibility
Eligible applicants
Business
- Small businesses
- For-profit organizations other than small businesses
Nonprofit
- Nonprofits non-higher education with 501(c)(3)
- Other Native American tribal organizations
- Nonprofits non-higher education without 501(c)(3)
Education
- Public and state institutions of higher education
- Independent school districts
- Private institutions of higher education
Government
- County governments
- Special district governments
- Federally recognized Native American tribal governments
- State governments
- City or township governments
- Public and Indian housing authorities
Miscellaneous
- Other
Additional information
Grantor contact information
Description
pilotstudies@mail.nih.gov
Documents
| File name | Description | Last updated |
|---|---|---|
| PAR-28-093-Full-Announcement.html | PAR-28-093-Full-Announcement.html | Oct 19, 2026 12:01 PM UTC |
Link to additional information
--
Closing: July 16, 2029
Award
$--
Program Funding
--
Expected awards
$--
Award Minimum
$450,000
Award Maximum
Funding opportunity number:
PAR-28-093
Cost sharing or matching requirement:
Funding instrument type:
Grant
Opportunity Category:
Discretionary
Opportunity Category Explanation:
Category of Funding Activity:
Health
Category Explanation:
History
Version:
1
Posted date:
October 19, 2026
Archive date:
September 16, 2029
