Skip to main content

Clinical Trials in Organ Transplantation in Children and Adults

Agency: National Institutes of Health

Assistance Listings: 93.855 -- Allergy and Infectious Diseases Research

Last Updated: June 24, 2026

Description

The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance its mission through the continued support of the Clinical Trials in Organ Transplantation in Children and Adults (CTOT-CA) program. The goal of the CTOT-CA is to improve the outcome of organ transplantation through clinical trials with mechanistic studies. The CTOT-CA will support multicenter clinical trials, with associated studies of immune mechanisms, in heart, lung, kidney, liver, and intestinal transplantation. The program will also support clinical trials of non-hematopoietic cellular transplantation as replacement therapies; vascularized composite tissue transplantation; and transplantation of bone marrow or mesenchymal stem cells, or of immunologically active cells, as adjuncts to organ transplantation. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.  

Eligibility

Eligible applicants

Miscellaneous

  • Other

Education

  • Public and state institutions of higher education
  • Independent school districts
  • Private institutions of higher education

Business

  • Small businesses
  • For-profit organizations other than small businesses

Government

  • Special district governments
  • Federally recognized Native American tribal governments
  • County governments
  • State governments
  • Public and Indian housing authorities
  • City or township governments

Nonprofit

  • Other Native American tribal organizations
  • Nonprofits non-higher education with 501(c)(3)
  • Nonprofits non-higher education without 501(c)(3)

Additional information

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Grantor contact information

Description

DAIT Transplantation Branch Clinical Trial Leadership Please contact via email.

Email

CTOT_CA_U01@mail.nih.gov

CTOT_CA_U01@mail.nih.gov

Documents

No documents are currently available.

Link to additional information

--

Forecasted

Estimated Post Date:

June 17, 2027

Estimated Application Due Date:

September 30, 2027

Estimated Due Date Description:

Not available

Estimated Award Date:

July 1, 2028

Estimated Project Start Date:

July 1, 2028

Fiscal Year:

2028

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$11,280,000

Program Funding

4

Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

RFA-AI-28-008

Cost sharing or matching requirement:

No

Funding instrument type:

Cooperative agreement

Opportunity Category:

Discretionary

Opportunity Category Explanation:

--

Category of Funding Activity:

Health

Category Explanation:

--

History

Version:

1

Forecast posted date:

June 24, 2026

Archive date:

--

HHS.gov

An official website of the U.S. Department of Health and Human Services

Looking for U.S. government information and services? Visit USA.gov