The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance its mission through the continued support of the Childhood Asthma in Urban Settings Clinical Research Network (CAUSE) network. The CAUSE network will support multi-site clinical studies and trials on the prevention and treatment of asthma in economically disadvantaged pediatric populations where disease burden is high. The objectives of the CAUSE network are to develop and test innovative hypotheses and strategies for asthma prevention; identify/test new treatment targets (including targets for intervention based on mechanisms of type 2 low asthma); and continue to explore the risk relationship between upper and lower airway. Using systems biology approaches, CAUSE will continue to identify disease endotypes that may be suitable targets for existing and novel therapeutic modalities. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.

Nonprofit

• Nonprofits non-higher education without 501(c)(3)
• Other Native American tribal organizations
• Nonprofits non-higher education with 501(c)(3)

Government

• State governments
• Public and Indian housing authorities
• City or township governments
• Special district governments
• County governments
• Federally recognized Native American tribal governments

Miscellaneous

• Other

Education

• Independent school districts
• Private institutions of higher education
• Public and state institutions of higher education

Business

• For-profit organizations other than small businesses
• Small businesses