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Immune Tolerance Network (UM1 Clinical Trial Required)

Agency: National Institutes of Health

Assistance Listings
  • 93.855 -- Allergy and Infectious Diseases Research

Open opportunityLast Updated: Oct 20, 2026

View version history on Grants.gov

The purpose of this notice of funding opportunity (NOFO) is to support applications to continue the Immune Tolerance Network (ITN). The primary objective of the Network is to develop tolerogenic therapies for immune-mediated disorders. The three main clinical areas of work are: 1) Allergic diseases and asthma; 2) Autoimmune diseases; and 3) Immune-mediated consequences of transplantation. The core functions of the ITN include designing, conducting, and sharing the results of clinical trials and performing integrated mechanistic studies.

Eligibility

Eligible applicants

Education

  • Independent school districts
  • Public and state institutions of higher education
  • Private institutions of higher education

Government

  • Public and Indian housing authorities
  • Federally recognized Native American tribal governments
  • State governments
  • City or township governments
  • County governments
  • Special district governments

Nonprofit

  • Nonprofits non-higher education with 501(c)(3)
  • Nonprofits non-higher education without 501(c)(3)
  • Other Native American tribal organizations

Miscellaneous

  • Other

Business

  • For-profit organizations other than small businesses
  • Small businesses

Additional information

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Grantor contact information

Description

Division of Allergy, Immunology and Transplantation ITN_UM1@mail.nih.gov

Email

ITN_UM1@mail.nih.gov

ITN_UM1@mail.nih.gov

Documents

File nameDescriptionLast updated
RFA-AI-28-005-Full-Announcement.html
RFA-AI-28-005-Full-Announcement.html
Oct 20, 2026 10:47 AM UTC

Link to additional information

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Closing: January 29, 2027

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$21,986,000

Program Funding

1

Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

RFA-AI-28-005

Cost sharing or matching requirement:

No

Funding instrument type:

Cooperative agreement

Opportunity Category:

Discretionary

Opportunity Category Explanation:

--

Category of Funding Activity:

Health

Category Explanation:

--

History

Version:

1

Posted date:

October 20, 2026

Archive date:

March 29, 2027

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