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​Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities​

Agency: Bureau of Arms Control and Nonproliferation

Assistance Listings: 19.224 -- Nonproliferation and Disarmament Fund

Last Updated: June 2, 2026

The Department of State’s Office of the Nonproliferation and Disarmament Fund (ACN/NDF) is pleased to announce an open competition for assistance awards through this Notice of Funding Opportunity (NOFO). ACN/NDF invites domestic non-profit/non-governmental organizations, educational institutions, and for-profit organizations to submit proposals for projects that will advance the mission of NDF’s efforts to identify, evaluate, and develop safeguards to counter the misuse risks enabled by the proliferation of chemical and biological Artificial Intelligence (AI) models (CBAIMs). Proposals may not exceed the total availability of funds under this NOFO. ACN/NDF welcomes proposals that fully address all or a clearly articulated, targeted subset of the key objectives of this NDF line of effort (Section II). Please indicate whether the proposal involves collaboration with a partner organization that is separately responding to this solicitation.

Eligibility

Eligible applicants

Nonprofit

  • Nonprofits non-higher education with 501(c)(3)
  • Nonprofits non-higher education without 501(c)(3)

Business

  • Small businesses
  • For-profit organizations other than small businesses

Education

  • Private institutions of higher education
  • Public and state institutions of higher education

Miscellaneous

  • Other

Additional information

U.S. Federal Government Entities are also eligible to apply. Organization must be based in the U.S. to be eligible.

Grantor contact information

Description

ACN/NDF Grants Mailbox

Email

ACN/NDF Grants Mailbox

acn-ndf-grants@state.gov

Documents

File nameDescriptionLast updated
NOFO_Sample_Performance_Indicators_Template.xlsx
Sample Performance Indicators Template
May 21, 2026 07:08 PM UTC
FY26_NDF_Project_Proposal_Template.docx
Project Proposal Template
May 21, 2026 07:08 PM UTC
Budget_Detail__Budget_Summary_-_TEMPLATE.xlsx
Detailed Budget Template
May 21, 2026 07:09 PM UTC
Budget_Narrative_Template.docx
Budget Narrative Template
May 21, 2026 07:09 PM UTC
Key_Personnel_Document.docx
Key Personnel Document
May 21, 2026 07:09 PM UTC
DFOP0018449_Solicitation.pdf
DFOP0018449 Solicitation
May 21, 2026 07:09 PM UTC

Link to additional information

Link to Opportunity in MyGrants

Closing: July 21, 2026

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$4,000,000

Program Funding

3

Expected awards

$--

Award Minimum

$4,000,000

Award Maximum

Funding opportunity number:

DFOP0018449

Cost sharing or matching requirement:

No

Funding instrument type:

Cooperative agreement

Opportunity Category:

Discretionary

Opportunity Category Explanation:

--

Category of Funding Activity:

Science technology and other research and development

Category Explanation:

--

History

Version:

2

Posted date:

May 21, 2026

Archive date:

--

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