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Centers for Structural Biology of HIV and Other Infectious Diseases (U54 Clinical Trial Not Allowed)

Agency: National Institutes of Health

Assistance Listings: 93.855 -- Allergy and Infectious Diseases Research

93.310 -- Trans-NIH Research Support

Last Updated: October 2, 2026

The purpose of this notice of funding opportunity (NOFO) is to support multidisciplinary consortia of structural biologists, microbiologists, and associated experts to solve complex biological structures related to the prevention, treatment, and cure of HIV and other infectious diseases. Centers are expected to facilitate new collaborations, leverage shared resources, offer services and resources to the research community, and train the next generation of scientists engaged in structural biology of infectious diseases.

Eligibility

Eligible applicants

Government

  • Federally recognized Native American tribal governments
  • City or township governments
  • Public and Indian housing authorities
  • State governments
  • Special district governments
  • County governments

Education

  • Public and state institutions of higher education
  • Private institutions of higher education
  • Independent school districts

Miscellaneous

  • Other

Nonprofit

  • Other Native American tribal organizations
  • Nonprofits non-higher education without 501(c)(3)
  • Nonprofits non-higher education with 501(c)(3)

Business

  • For-profit organizations other than small businesses
  • Small businesses

Additional information

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed. NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. See NIH Grants Policy Statement 16.8 Collaborative International Research Awards.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.

Grantor contact information

Description

National Institute of Allergy and Infectious Diseases (NIAID) BSPDAIDSNOFO@mail.nih.gov

Email

BSPDAIDSNOFO@mail.nih.gov

BSPDAIDSNOFO@mail.nih.gov

Documents

File nameDescriptionLast updated
RFA-AI-28-031-Full-Announcement.html
RFA-AI-28-031-Full-Announcement.html
Oct 2, 2026 12:28 PM UTC

Link to additional information

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Closing: May 28, 2027

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$33,000,000

Program Funding

--

Expected awards

$--

Award Minimum

$3,500,000

Award Maximum

Funding opportunity number:

RFA-AI-28-031

Cost sharing or matching requirement:

No

Funding instrument type:

Cooperative agreement

Opportunity Category:

Discretionary

Opportunity Category Explanation:

--

Category of Funding Activity:

Health

Category Explanation:

--

History

Version:

1

Posted date:

October 2, 2026

Archive date:

July 28, 2027

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