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NIH Director’s Early Independence Award (DP5 Clinical Trial Optional)

Agency: National Institutes of Health

Assistance Listings: 93.310 -- Trans-NIH Research Support

Last Updated: June 26, 2026
The NIH Director's Early Independence Award helps talented new researchers begin their own independent research program soon after finishing their doctoral degree or clinical training, without first doing postdoctoral training.The award accepts applications on any topic fitting the NIH mission. It is part of the NIH Common Fund's High-Risk, High-Reward Research program.

Eligibility

Eligible applicants

Business

  • Small businesses
  • For-profit organizations other than small businesses

Education

  • Private institutions of higher education
  • Public and state institutions of higher education
  • Independent school districts

Government

  • Public and Indian housing authorities
  • Special district governments
  • County governments
  • State governments
  • Federally recognized Native American tribal governments
  • City or township governments

Nonprofit

  • Other Native American tribal organizations
  • Nonprofits non-higher education without 501(c)(3)
  • Nonprofits non-higher education with 501(c)(3)

Miscellaneous

  • Other

Additional information

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Grantor contact information

Description

NIH Director's Early Independence Award Program EarlyIndependence@od.nih.gov

Email

EarlyIndependence@od.nih.gov

EarlyIndependence@od.nih.gov

Documents

File nameDescriptionLast updated
RFA-RM-27-004-Full-Announcement.html
RFA-RM-27-004-Full-Announcement.html
Jun 26, 2026 03:38 PM UTC

Link to additional information

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Closing: September 10, 2026

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$5,700,000

Program Funding

10

Expected awards

$350,000

Award Minimum

$350,000

Award Maximum

Funding opportunity number:

RFA-RM-27-004

Cost sharing or matching requirement:

No

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

--

Category of Funding Activity:

Health

Category Explanation:

--

History

Version:

1

Posted date:

June 26, 2026

Archive date:

November 10, 2026

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