Seed Instrumentation Support (SIS) Program (S10 Clinical Trial Not Allowed)
Agency: National Institutes of Health
Assistance Listings: 93.351 -- Research Infrastructure Programs
93.855 -- Allergy and Infectious Diseases Research
93.310 -- Trans-NIH Research Support
93.866 -- Aging Research
Last Updated: June 25, 2026
Description
This Notice of Funding Opportunity (NOFO) aims to build new research capacity and develop a sustainable research program by supporting the purchase of a single commercially available biomedical research instrument currently unavailable in the institution. Instruments funded through this program must be shared among the users to create new research opportunities, enable reproducible data generation, encourage collaborative research and training, and strengthen long-term research capabilities. The minimum award is $50,000. While there is no limit on the total cost of the instrument, the maximum award is $400,000.
Eligibility
Eligible applicants
Government
- City or township governments
- County governments
- Public and Indian housing authorities
- Federally recognized Native American tribal governments
- State governments
- Special district governments
Business
- Small businesses
- For-profit organizations other than small businesses
Nonprofit
- Nonprofits non-higher education without 501(c)(3)
- Other Native American tribal organizations
- Nonprofits non-higher education with 501(c)(3)
Education
- Private institutions of higher education
- Independent school districts
- Public and state institutions of higher education
Miscellaneous
- Other
Additional information
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Grantor contact information
Description
Office of Research Infrastructure Programs (ORIP)
odsig@mail.nih.gov
xiang-ning.li@nih.gov
Documents
| File name | Description | Last updated |
|---|---|---|
| PAR-27-021-Full-Announcement.html | PAR-27-021-Full-Announcement.html | Jun 25, 2026 04:53 PM UTC |
Link to additional information
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Closing: July 1, 2028
Award
$--
Program Funding
--
Expected awards
$50,000
Award Minimum
$400,000
Award Maximum
Funding opportunity number:
PAR-27-021
Cost sharing or matching requirement:
No
Funding instrument type:
Grant
Opportunity Category:
Discretionary
Opportunity Category Explanation:
--
Category of Funding Activity:
Health
Category Explanation:
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History
Version:
1
Posted date:
June 25, 2026
Archive date:
September 1, 2028
