INCLUDE Project: Exploratory/Developmental Research Awards for Down syndrome (R21 Clinical Trial Not Allowed)
Agency: National Institutes of Health
Assistance Listings
- 93.310 -- Trans-NIH Research Support
- 93.233 -- National Center on Sleep Disorders Research
- 93.837 -- Cardiovascular Diseases Research
- 93.121 -- Oral Diseases and Disorders Research
- 93.395 -- Cancer Treatment Research
- 93.865 -- Child Health and Human Development Extramural Research
- 93.867 -- Vision Research
- 93.855 -- Allergy and Infectious Diseases Research
- 93.846 -- Arthritis, Musculoskeletal and Skin Diseases Research
- 93.351 -- Research Infrastructure Programs
- 93.839 -- Blood Diseases and Resources Research
- 93.173 -- Research Related to Deafness and Communication Disorders
- 93.840 -- Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders
- 93.866 -- Aging Research
- 93.879 -- Medical Library Assistance
- 93.838 -- Lung Diseases Research
Open opportunityLast Updated: May 13, 2026
View version history on Grants.gov
Description
The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. This Notice of Funding Opportunity (NOFO) invites researchers to submit applications for support of new exploratory and developmental research projects that address critical needs for Down syndrome projects, as articulated in the INCLUDE Project objectives. For example, such projects could assess the feasibility of a novel area of investigation or a new experimental system that has the potential to enhance...
health-related research. Another example could include the unique and innovative use of an existing methodology to explore a new scientific area. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research.
Eligibility
Eligible applicants
Government
- Special district governments
- State governments
- City or township governments
- County governments
- Public and Indian housing authorities
- Federally recognized Native American tribal governments
Nonprofit
- Other Native American tribal organizations
- Nonprofits non-higher education without 501(c)(3)
- Nonprofits non-higher education with 501(c)(3)
Business
- For-profit organizations other than small businesses
- Small businesses
Miscellaneous
- Other
Education
- Independent school districts
- Private institutions of higher education
- Public and state institutions of higher education
Additional information
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Grantor contact information
Description
The INCLUDE Project
DownSyndromeINCLUDE@mail.nih.gov
DownSyndromeINCLUDE@mail.nih.gov
Documents
| File name | Description | Last updated |
|---|---|---|
| RFA-OD-27-003-Full-Announcement.html | RFA-OD-27-003-Full-Announcement.html | May 12, 2026 03:21 PM UTC |
Link to additional information
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Closing: June 15, 2028
Award
$1,000,000
Program Funding
5
Expected awards
$--
Award Minimum
$200,000
Award Maximum
Funding opportunity number:
RFA-OD-27-003
Cost sharing or matching requirement:
No
Funding instrument type:
Grant
Opportunity Category:
Discretionary
Opportunity Category Explanation:
--
Category of Funding Activity:
Health
Category Explanation:
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History
Version:
1
Posted date:
May 12, 2026
Archive date:
August 14, 2028
