Opportunity Listing - SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional)

SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional)

Agency: National Institutes of Health

Assistance Listings: 93.853 -- Extramural Research Programs in the Neurosciences and Neurological Disorders

93.837 -- Cardiovascular Diseases Research

93.859 -- Biomedical Research and Research Training

93.847 -- Diabetes, Digestive, and Kidney Diseases Extramural Research

93.866 -- Aging Research

93.838 -- Lung Diseases Research

93.839 -- Blood Diseases and Resources Research

93.865 -- Child Health and Human Development Extramural Research

93.172 -- Human Genome Research

93.233 -- National Center on Sleep Disorders Research

93.143 -- NIEHS Superfund Hazardous Substances_Basic Research and Education

93.351 -- Research Infrastructure Programs

93.307 -- Minority Health and Health Disparities Research

93.273 -- Alcohol Research Programs

93.840 -- Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders

93.394 -- Cancer Detection and Diagnosis Research

93.855 -- Allergy and Infectious Diseases Research

93.846 -- Arthritis, Musculoskeletal and Skin Diseases Research

93.350 -- National Center for Advancing Translational Sciences

93.113 -- Environmental Health

93.121 -- Oral Diseases and Disorders Research

93.286 -- Discovery and Applied Research for Technological Innovations to Improve Human Health

93.242 -- Mental Health Research Grants

93.173 -- Research Related to Deafness and Communication Disorders

93.395 -- Cancer Treatment Research

93.313 -- NIH Office of Research on Women's Health

93.393 -- Cancer Cause and Prevention Research

93.867 -- Vision Research

Last Updated: May 28, 2026

View version history on Grants.gov

Description

The Commercialization Readiness Pilot (CRP) program helps small business concerns (SBCs) move NIH-funded SBIR or STTR projects from late-stage development to commercialization. The CRP supports later-stage research and development (R&D) and/or technical assistance that Phase II and Phase IIB Strategic Breakthrough awards do not typically support. This includes:Independent replication or confirmation of key studiesIND- or IDE-enabling studiesClinical studiesManufacturing scale-up and related quality activitiesRegulatory and other specialized technical supportSBCs may subcontract (outsource) a significant amount of the work in a CRP to meet the project goals.

Eligibility

Eligible applicants

Business

Small businesses
For-profit organizations other than small businesses

Government

State governments
County governments
Public and Indian housing authorities
Special district governments
Federally recognized Native American tribal governments
City or township governments

Miscellaneous

Other

Nonprofit

Other Native American tribal organizations
Nonprofits non-higher education without 501(c)(3)
Nonprofits non-higher education with 501(c)(3)

Education

Private institutions of higher education
Public and state institutions of higher education
Independent school districts

Additional information

Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir.gov/apply) are eligible to submit applications for this opportunity.Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Unfunded international collaborations or unfunded foreign components, as defined in the NIH Grants Policy Statement, may be allowed.

Grantor contact information

Description

NIH SEED (Small business Education and Entrepreneurial Development) SEEDinfo@nih.gov

Email

NIH SEED (Small business Education and Entrepreneurial Development)

SEEDinfo@nih.gov

Documents

File name	Description	Last updated
PAR-27-098-Full-Announcement.html	PAR-27-098-Full-Announcement.html	May 28, 2026 07:03 PM UTC

Link to additional information

Closing: April 5, 2027

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$--

Program Funding

Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

PAR-27-098

Cost sharing or matching requirement:

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

Category of Funding Activity:

Health

Category Explanation:

History

Version:

Posted date:

May 28, 2026

Archive date:

June 4, 2029