Resource-Related Research Projects for Development of Models and Related Materials for Studying Human Health and Diseases (R24 Clinical Trials Not Allowed)
Agency: National Institutes of Health
Assistance Listings
- 93.351 -- Research Infrastructure Programs
Open opportunityLast Updated: May 13, 2026
Important dates
- Closing: September 28, 2028
Award details
- Expected project funding: $5,000,000
- Expected awards: 6
Award min.
Not specified
Award max.
Not specified
- Funding opportunity number:RFA-OD-25-010
- Cost sharing or matching requirement:No
- Funding instrument type:
- Grant
- Opportunity Category:Discretionary
- Opportunity Category Explanation:Not specified
- Category of Funding Activity:
- Health
- Category Explanation:Not specified
History
- Posted date: December 5, 2025
- Archive date: November 2, 2028
- Version: 2
Summary
Jump to documentsThe Office of Research Infrastructure Programs (ORIP) encourages grant applications aimed at developing, characterizing, or improving research models of human health and diseases; developing biology based new approach methodologies (NAMs) applicable to human health and diseases; or improving access to information about or generated from the use of models of human disease. The models, including NAMs, and related biological materials developed must be broadly applicable to the scientific interests of two or more NIH Institutes or Centers (ICs) and must evaluate diseases and processes that impact multiple...
organ systems in order to align with the ORIP"s NIH-wide mission and programs. Applications must describe the need for and the potential impact of the proposed resources on the research community across a range of scientific disciplines supported by multiple NIH ICs. Applications to develop models that relate strictly to a specific disease or a select area of research or that do not have a broad impact on the NIH-wide research community will not be accepted. Projects that predominantly address the research interests of one NIH IC but are only peripherally related to the research interests of other ICs will also not be accepted, if submitted in response to this notice of funding opportunity (NOFO).
Eligibility
Government
- City or township governments
- County governments
- Federally recognized Native American tribal governments
- State governments
Miscellaneous
- Other
Nonprofit
- Nonprofits non-higher education without 501(c)(3)
- Nonprofits non-higher education with 501(c)(3)
Education
- Private institutions of higher education
- Public and state institutions of higher education
Business
- For-profit organizations other than small businesses
- Small businesses
Additional information on eligibility
Refer to Section III. Eligibility Information of the NOFO for additional information on eligibility.Foreign Organizations/Foreign CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Documents
| File name | Description | Last updated |
|---|---|---|
| RFA-OD-25-010-Full-Announcement.html | RFA-OD-25-010-Full-Announcement.html | Dec 5, 2025 06:50 PM UTC |
| RFA-OD-25-010-Revised-Full-Announcement.html | RFA-OD-25-010-Revised-Full-Announcement.html | Dec 24, 2025 03:16 PM UTC |
Agency contact information
Email: ORIPDCM@mail.nih.gov
ORIPDCM@mail.nih.gov
Office of Research Infrastructure Programs (ORIP)
ORIPDCM@mail.nih.gov
Link to additional information
No additional information is available
