Animal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed)
Agency: National Institutes of Health
Assistance Listings: 93.351 -- Research Infrastructure Programs
Last Updated: June 9, 2025
Description
The Office of Research Infrastructure Programs at Division of Program Coordination, Planning and Strategic Initiatives intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications to provide support for the Animal and Biological Material Resource Centers. The P40 mechanism supports projects to develop and maintain animal (mammalian and nonmammalian) models, related animal or biological material resources, and new approach methodologies (NAMs) available to all qualified investigators without regard to the scientific disciplines or disease orientations of their research activities or specifically directed to a categorical program.
This Notice is being provided now to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO will have nine application cycles. The NOFO is expected to be published in December 2025, with an expected application due date in February 2026. Details of the planned NOFO are provided below.
Research Initiative Details
With this intended reissue of the P40 funding opportunity, ORIP seeks to provide support for special colonies of laboratory animals and associated services, as well as other resources such as informatics tools, reagents, cultures (cells, tissues, and organs) and genetic stocks that serve the biomedical research community in a variety of research areas on a local, regional, and national basis.
The goal of projects supported by this NOFO is to provide research resources that facilitate optimization and enhancement of scientific rigor, transparency, and experimental reproducibility of biomedical research.
Collecting, generating, and distributing animal models and providing related services render these resources more accessible to the research community and eliminate costly redundant efforts. Of special interest of the announcement is a requirement of the Center’s close coordination with efforts to develop new approach methodologies (NAMS) that complement traditional animal-based research. These include cell culture, organoids, computational models, and microphysiological systems. Proposed resources should emphasize use of broadly applicable, interdisciplinary validation tools that enhance the predictive power of human disease models and support their integration with NAMs.
Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the P40 activity code. Investigators with expertise and insights into animal and non-animal models of human diseases are encouraged to begin to consider applying for this NOFO. In addition, collaborative investigations combining expertise in genetics and biology as well as research databases will be encouraged; these investigators should also begin considering applying for this application.
Eligibility
Eligible applicants
Business
- Small businesses
- For-profit organizations other than small businesses
Government
- County governments
- State governments
- Public and Indian housing authorities
- Federally recognized Native American tribal governments
Nonprofit
- Other Native American tribal organizations
- Nonprofits non-higher education with 501(c)(3)
Education
- Independent school districts
- Public and state institutions of higher education
- Private institutions of higher education
Additional information
Grantor contact information
Description
Oleg.mirochnitchenko@nih.gov
Documents
No documents are currently available here
Link to additional information
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Forecasted
Estimated Post Date:
December 18, 2025
Estimated Application Due Date:
February 18, 2026
Estimated Due Date Description:
Not available
Estimated Award Date:
December 1, 2026
Estimated Project Start Date:
December 11, 2026
Fiscal Year:
2027
Award
$1,300,000
Program Funding
2
Expected awards
$--
Award Minimum
$--
Award Maximum
Funding opportunity number:
TEMP-30965
Cost sharing or matching requirement:
Funding instrument type:
Grant
Opportunity Category:
Discretionary
Opportunity Category Explanation:
Category of Funding Activity:
Health
Category Explanation:
History
Version:
1
Forecast posted date:
June 9, 2025
Archive date:
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