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Animal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed)

Agency: National Institutes of Health

Assistance Listings: 93.351 -- Research Infrastructure Programs

Last Updated: June 9, 2025

Description

The Office of Research Infrastructure Programs at Division of Program Coordination, Planning and Strategic Initiatives intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications to provide support for the Animal and Biological Material Resource Centers. The P40 mechanism supports projects to develop and maintain animal (mammalian and nonmammalian) models, related animal or biological material resources, and new approach methodologies (NAMs) available to all qualified investigators without regard to the scientific disciplines or disease orientations of their research activities or specifically directed to a categorical program.


This Notice is being provided now to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO will have nine application cycles. The NOFO is expected to be published in December 2025, with an expected application due date in February 2026. Details of the planned NOFO are provided below.


Research Initiative Details

With this intended reissue of the P40 funding opportunity, ORIP seeks to provide support for special colonies of laboratory animals and associated services, as well as other resources such as informatics tools, reagents, cultures (cells, tissues, and organs) and genetic stocks that serve the biomedical research community in a variety of research areas on a local, regional, and national basis.


The goal of projects supported by this NOFO is to provide research resources that facilitate optimization and enhancement of scientific rigor, transparency, and experimental reproducibility of biomedical research.


Collecting, generating, and distributing animal models and providing related services render these resources more accessible to the research community and eliminate costly redundant efforts. Of special interest of the announcement is a requirement of the Center’s close coordination with efforts to develop new approach methodologies (NAMS) that complement traditional animal-based research. These include cell culture, organoids, computational models, and microphysiological systems. Proposed resources should emphasize use of broadly applicable, interdisciplinary validation tools that enhance the predictive power of human disease models and support their integration with NAMs.


Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the P40 activity code. Investigators with expertise and insights into animal and non-animal models of human diseases are encouraged to begin to consider applying for this NOFO. In addition, collaborative investigations combining expertise in genetics and biology as well as research databases will be encouraged; these investigators should also begin considering applying for this application.

Eligibility

Eligible applicants

Business

  • Small businesses
  • For-profit organizations other than small businesses

Government

  • County governments
  • State governments
  • Public and Indian housing authorities
  • Federally recognized Native American tribal governments

Nonprofit

  • Other Native American tribal organizations
  • Nonprofits non-higher education with 501(c)(3)

Education

  • Independent school districts
  • Public and state institutions of higher education
  • Private institutions of higher education

Additional information

Grantor contact information

Description

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Email

Oleg.mirochnitchenko@nih.gov

Oleg.mirochnitchenko@nih.gov

Documents

No documents are currently available here

Link to additional information

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Forecasted

Estimated Post Date:

December 18, 2025

Estimated Application Due Date:

February 18, 2026

Estimated Due Date Description:

Not available

Estimated Award Date:

December 1, 2026

Estimated Project Start Date:

December 11, 2026

Fiscal Year:

2027

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$1,300,000

Program Funding

2

Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

TEMP-30965

Cost sharing or matching requirement:

No

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

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Category of Funding Activity:

Health

Category Explanation:

--

History

Version:

1

Forecast posted date:

June 9, 2025

Archive date:

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