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PRIMED-AI: Multi-use Framework Playbooks (UG3 Clinical Trial Not Allowed)

Agency: National Institutes of Health

Assistance Listings: 93.310 -- Trans-NIH Research Support

Last Updated: June 6, 2025

Description

The NIH Common Fund, with other NIH Institutes and Centers (ICs), intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for the Precision Medicine with Artificial Intelligence - Integrating Imaging with Multimodal Data (PRIMED-AI) program, which seeks to develop innovative, reliable, and cost-effective AI-based tools that integrate clinical imaging with other health data types to enhance personalized medicine for patients with chronic and other health conditions. The program’sPlaybook initiative will fund the development and initial testing of discrete projects that deliver “playbooks” of frameworks for responsible use of PRIMED-AI models, error mitigation and technical management of data and algorithms, data ontology/linkage, and preparation for regulatory approval​ (e.g., FDA). Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the UG3 activity code. Investigators with expertise and insights into AI-driven integration of clinical imaging with other complex and multiscale health data are encouraged to begin to consider applying for this new NOFO. In addition, collaborative investigations combining expertise in harmonization processes for appropriate development and validation of multimodal AI tools to develop AI-based technologies leveraging multimodal data will be encouraged and these investigators should also begin considering applying for this application.

Eligibility

Eligible applicants

Education

  • Public and state institutions of higher education
  • Private institutions of higher education
  • Independent school districts

Government

  • Federally recognized Native American tribal governments
  • Public and Indian housing authorities
  • County governments
  • State governments

Business

  • Small businesses
  • For-profit organizations other than small businesses

Nonprofit

  • Other Native American tribal organizations
  • Nonprofits non-higher education with 501(c)(3)

Additional information

Grantor contact information

Description

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Email

ODPRIMED-AI@od.nih.gov

ODPRIMED-AI@od.nih.gov

Documents

No documents are currently available here

Link to additional information

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Forecasted

Estimated Post Date:

July 1, 2025

Estimated Application Due Date:

November 1, 2025

Estimated Due Date Description:

Not available

Estimated Award Date:

September 1, 2026

Estimated Project Start Date:

September 1, 2026

Fiscal Year:

2026

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$650,000

Program Funding

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Expected awards

$--

Award Floor

$--

Award Ceiling

Funding opportunity number:

NOT-RM-25-020

Cost sharing or matching requirement:

No

Funding instrument type:

Cooperative agreement

Opportunity Category:

Discretionary

Opportunity Category Explanation:

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Category of Funding Activity:

Health

Category Explanation:

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History

Version:

1

Posted date:

June 6, 2025

Archive date:

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