PRIMED-AI: Data-to-Model Academic-Industrial Partnerships (D2M-AIP) for Precision Medicine with AI: Integrating Imaging with Multimodal Data (UG3/UH3 Clinical Trial Optional)
Agency: National Institutes of Health
Assistance Listings: 93.310 -- Trans-NIH Research Support
Last Updated: June 30, 2026
Description
The overarching goal of this notice of funding opportunity (NOFO) and its companion opportunities is to establish the Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) Program to support development of innovative, reliable, cost-effective, and sustainable multimodal AI-based clinical decision support (CDS) tools. PRIMED-AI CDS tools are based on the integration of clinical imaging with other types of multimodal health data to enhance care for patients with a wide range of health conditions. The PRIMED-AI Program seeks to catalyze the adoption of AI-based CDS tools...
into clinical workflows to enable novel personalized medicine strategies that address significant health challenges. The purpose of this Notice of Funding Opportunity (NOFO) is to catalyze the development and testing of Artificial Intelligence (AI)-enabled, image-centered, multimodal Clinical Decision Support (CDS) tools, developed in pursuance as Software as a Medical Device (SaMD). These projects are expected to have high potential for demonstrable, positive impact on patient outcomes and/or healthcare processes.
Eligibility
Eligible applicants
Government
- State governments
- City or township governments
- Special district governments
- Federally recognized Native American tribal governments
- Public and Indian housing authorities
- County governments
Education
- Independent school districts
- Public and state institutions of higher education
- Private institutions of higher education
Nonprofit
- Nonprofits non-higher education without 501(c)(3)
- Other Native American tribal organizations
- Nonprofits non-higher education with 501(c)(3)
Miscellaneous
- Other
Business
- Small businesses
- For-profit organizations other than small businesses
Additional information
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Grantor contact information
Description
PRIMED-AI Program
ODPRIMED-AI@od.nih.gov
ODPRIMED-AI@od.nih.gov
Documents
| File name | Description | Last updated |
|---|---|---|
| RFA-RM-27-012-Full-Announcement.html | RFA-RM-27-012-Full-Announcement.html | Jun 30, 2026 03:02 PM UTC |
Link to additional information
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Closing: October 19, 2026
Award
$--
Program Funding
8
Expected awards
$--
Award Minimum
$--
Award Maximum
Funding opportunity number:
RFA-RM-27-012
Cost sharing or matching requirement:
No
Funding instrument type:
Cooperative agreement
Opportunity Category:
Discretionary
Opportunity Category Explanation:
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Category of Funding Activity:
Health
Category Explanation:
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History
Version:
1
Posted date:
June 30, 2026
Archive date:
December 18, 2026
