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BRAIN Initiative: Theories, Models and Methods for Analysis of Complex Data from the Brain

Agency: National Institutes of Health

Assistance Listings: 93.279 -- Drug Use and Addiction Research Programs

93.372 -- 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies

Last Updated: May 22, 2025

Description

The National Institute on Drug Abuse (NIDA), with other NIH Institutes and Centers (ICs) the National Eye Institute (NEI), National Institute on Aging (NIA), National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Institute of Biomedical Imaging and Bioengineering (NIBIB), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institute on Deafness and Other Communication Disorders (NIDCD), National Institute of Neurological Disorders and Stroke (NINDS), National Institute of Mental Health (NIMH), National Center for Complementary and Integrative Health (NCCIH) and Office of Behavioral and Social Sciences Research (OBSSR), intends to publish a Notice of Funding Opportunity (NOFO) as a part of the BRAIN Initiative to solicit applications for research on Theories, Models and Methods for Analysis of Complex Data (TMM). This program provides support for the development of computational tools (theories, models, methods) for understanding dynamic brain circuits, which will be made broadly accessible to the greater research community. This program supports applications focused on tool building and dissemination in the domain of theories about neural circuit mechanisms, models of circuit structure and function, and/or computational methods of analysis spanning the scale of neurons and firing rates (or proxies thereof), or finer resolution. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the R01 activity code. Investigators with expertise and insights into this area of computational models, theories and models of neural computations, and AI are encouraged to begin to consider applying for this new NOFO. In addition, collaborative investigations combining expertise in mechanistic, interpretable and predictive models of neural dynamics, and neural circuit function, will be encouraged, and these investigators should also begin considering applying for this application.

Eligibility

Eligible applicants

Education

  • Private institutions of higher education
  • Public and state institutions of higher education
  • Independent school districts

Business

  • Small businesses
  • For-profit organizations other than small businesses

Government

  • Public and Indian housing authorities
  • County governments
  • State governments
  • Federally recognized Native American tribal governments

Nonprofit

  • Nonprofits non-higher education with 501(c)(3)
  • Other Native American tribal organizations

Additional information

Grantor contact information

Description

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Email

Jessica.mollick@nih.gov

Jessica.mollick@nih.gov

Documents

No documents are currently available here

Link to additional information

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Forecasted

Estimated Post Date:

November 5, 2025

Estimated Application Due Date:

February 5, 2026

Estimated Due Date Description:

Not available

Estimated Award Date:

December 1, 2026

Estimated Project Start Date:

December 1, 2026

Fiscal Year:

2027

Application process

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Award

$6,000,000

Program Funding

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Expected awards

$--

Award Floor

$--

Award Ceiling

Funding opportunity number:

FOR-DA-27-006

Cost sharing or matching requirement:

No

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

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Category of Funding Activity:

Health

Category Explanation:

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History

Version:

1

Posted date:

May 22, 2025

Archive date:

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