The National Institute on Drug Abuse (NIDA) intends to publish a Notice of Funding Opportunity (NOFO) to support research on the discovery and development of interventions to prevent and treat substance use disorders (SUDs) and overdose. This includes preclinical and clinical research studies that will have high impact and quickly yield the necessary results to advance candidate interventions closer to regulatory approval or clinical adoption. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the UG3/UH3 activity code. Investigators with expertise and insights in the areas of SUD therapeutics discovery and development are encouraged to begin to consider applying for this new NOFO. Collaborative investigations combining expertise in pharmacology, toxicology, medicinal chemistry, neuromodulation, digital interventions, clinical trials, regulatory science, among others, will be encouraged, and these investigators should also begin considering applying for this application. 

Business

• For-profit organizations other than small businesses
• Small businesses

Government

• Federally recognized Native American tribal governments
• County governments
• Public and Indian housing authorities
• State governments

Education

• Private institutions of higher education
• Public and state institutions of higher education
• Independent school districts

Nonprofit

• Other Native American tribal organizations
• Nonprofits non-higher education with 501(c)(3)