The National Institute on Deafness and Other Communication Disorders intends to reissue a Notice of Funding Opportunity (NOFO, prior funding opportunity PAR-22-025) to solicit applications for Clinical Research Center Grants in the mission areas of hearing, balance, smell, taste, voice, speech, or language. For this announcement, Clinical Research is defined as research involving individuals with a sensory and/or communication disorder, or data/tissues from individuals with a sensory and/or communication disorder. The Clinical Research Center provides a vehicle for integrated, multidisciplinary approaches to critical clinical research questions that advance the study of prevention, pathogenesis, pathophysiology, diagnosis, treatment, management or epidemiology of a disease or disorder of hearing, balance, smell, taste, voice, speech, or language. The P50 provides an avenue for forming a multidisciplinary team that is intended to bring innovative ideas and distinct perspectives to the generation and evaluation of high impact solutions to complex clinical problems. Responsive applications must include a multidisciplinary team collaborating on a synergistic set of 3-4 research projects addressing a unifying theme. The synergistic and substantial integration of research projects is intended to generate breakthrough solutions to the unifying problem. The research efforts are further supported by an administrative core and 1-2 optional scientific cores to ensure rigorous and efficient progress towards the center’s unifying theme. Overall, the clinical research center provides a whole that will have impact beyond the sum of its parts. Applications may propose a low-risk clinical trial but are not required to (optional).

Business

• For-profit organizations other than small businesses
• Small businesses

Education

• Independent school districts
• Private institutions of higher education
• Public and state institutions of higher education

Government

• Public and Indian housing authorities
• County governments
• Federally recognized Native American tribal governments
• State governments

Nonprofit

• Other Native American tribal organizations
• Nonprofits non-higher education with 501(c)(3)