Single-Site Investigator-Initiated Clinical Trials (R61/R33 Clinical Trial Required)
Agency: National Institutes of Health
Assistance Listings: 93.837 -- Cardiovascular Diseases Research
93.233 -- National Center on Sleep Disorders Research
93.838 -- Lung Diseases Research
93.840 -- Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders
93.839 -- Blood Diseases and Resources Research
Last Updated: May 9, 2025
Description
The NHLBI intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications to develop and implement investigator-initiated single site clinical trials including efficacy, comparative effectiveness, pragmatic and/or implementation research clinical trials. Trials using innovative designs such as platform trials, adaptive, and Bayesian designs are encouraged. These trials may include ones that test different therapeutic, behavioral, and/or prevention strategies. Trials for which this NOFO applies must be relevant to the research mission of the NHLBI and meet the NIH definition of a clinical trial.
Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the R61/R33 activity code. Investigators with expertise and insights into this area are encouraged to begin to consider applying for this NOFO.
Eligibility
Eligible applicants
Government
- Public and Indian housing authorities
- Federally recognized Native American tribal governments
- County governments
Education
- Independent school districts
- Private institutions of higher education
- Public and state institutions of higher education
Nonprofit
- Other Native American tribal organizations
- Nonprofits non-higher education with 501(c)(3)
Business
- For-profit organizations other than small businesses
- Small businesses
Additional information
Grantor contact information
Description
rosenbey@nhlbi.nih.gov
Documents
No documents are currently available here
Link to additional information
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Forecasted
Estimated Post Date:
July 11, 2025
Estimated Application Due Date:
October 13, 2025
Estimated Due Date Description:
Not available
Estimated Award Date:
May 1, 2026
Estimated Project Start Date:
July 1, 2026
Fiscal Year:
2026
Award
$--
Program Funding
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Expected awards
$--
Award Floor
$--
Award Ceiling
Funding opportunity number:
FON-HL-25-028
Cost sharing or matching requirement:
Funding instrument type:
Grant
Opportunity Category:
Discretionary
Opportunity Category Explanation:
Category of Funding Activity:
Health
Category Explanation:
History
Version:
1
Posted date:
May 9, 2025
Archive date:
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