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Trailblazer Award for New and Early Stage Investigators (R21 Clinical Trial Optional)

Agency: National Institutes of Health

Assistance Listings: 93.867 -- Vision Research

93.286 -- Discovery and Applied Research for Technological Innovations to Improve Human Health

93.866 -- Aging Research

Last Updated: January 8, 2025

Funding opportunity

Summary

This Trailblazer Award is an opportunity for NIH-defined New and Early Stage Investigators (https://grants.nih.gov/policy/early-investigators/index.htm) to pursue research programs that integrate engineering and the physical sciences with the life and/or biomedical sciences. A Trailblazer project may be exploratory, developmental, proof of concept, or high risk-high impact, and may be technology design-directed, discovery-driven, or hypothesis-driven. Importantly, applicants must propose research approaches for which there are minimal or no preliminary data. A distinct feature for this FOA is that...

Eligibility

Eligible applicants

Nonprofits non-higher education with 501(c)(3)

Public and Indian housing authorities

State governments

Small businesses

Independent school districts

Private institutions of higher education

Special district governments

Other

Other Native American tribal organizations

County governments

Federally recognized Native American tribal governments

For-profit organizations other than small businesses

Nonprofits non-higher education without 501(c)(3)

Public and state institutions of higher education

City or township governments

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Documents

File nameDescriptionLast updated
PA-25-169-Full-Announcement.html
PA-25-169 Full Announcement Text
Jan 8, 2025 04:16 PM UTC

Closing: January 7, 2026

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

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Program Funding

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Expected awards

$--

Award Ceiling

$--

Award Floor

Funding opportunity number:

PA-25-169

Cost sharing or matching requirement:

No

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

--

Category of Funding Activity:

Health

Category Explanation:

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History

Version:

1

Posted date:

January 8, 2025

Archive date:

February 12, 2026

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