Advanced Development and Validation of Emerging Biospecimen Science Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)
Agency: National Institutes of Health
Assistance Listings: 93.394 -- Cancer Detection and Diagnosis Research
Last Updated: December 16, 2024
Description
Through this Notice of Funding Opportunity (NOFO), National Cancer Institute (NCI) solicits grant applications proposing exploratory research projects focused on further development and validation of emerging technologies that improve the quality and handling of samples used for cancer research or clinical care. Through this NOFO, NCI will support the development of tools, devices, assays, and associated methods for the collection, handling, processing, preservation, or storage of cancer-relevant biospecimens and their derivatives. This includes tools with new capabilities to preserve or protect...
sample integrity, or establish verification criteria for quality assessment/quality control and address issues related to pre-analytical degradation of of targeted analytes. Major feasibility gaps for the technology or methodology should have already been overcome, as demonstrated by supportive preliminary data, but the tool requires further development and rigorous validation. These technologies are expected to accelerate and/or enhance research in cancer biology, early detection and screening, clinical diagnosis, treatment, or epidemiology and/or address issues associated with cancer health disparities.
This funding opportunity is part of a broader NCI-sponsored Innovative Molecular Analysis Technologies (IMAT) Program.
Eligibility
Eligible applicants
Nonprofit
- Nonprofits non-higher education without 501(c)(3)
- Nonprofits non-higher education with 501(c)(3)
- Other Native American tribal organizations
Government
- Public and Indian housing authorities
- County governments
- Special district governments
- Federally recognized Native American tribal governments
- State governments
- City or township governments
Education
- Private institutions of higher education
- Public and state institutions of higher education
- Independent school districts
Business
- Small businesses
- For-profit organizations other than small businesses
Miscellaneous
- Other
Additional information
Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Grantor contact information
Description
NIH Grants Information
grantsinfo@nih.gov
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
Documents
| File name | Description | Last updated |
|---|---|---|
| RFA-CA-25-004-Full-Announcement.html | RFA-CA-25-004 Full Announcement Text | Dec 16, 2024 04:35 PM UTC |
Link to additional information
https://grants.nih.gov/grants/guide/rfa-files/RFA-CA-25-004.html
Closing: October 3, 2025
Award
$300,000
Program Funding
2
Expected awards
$--
Award Minimum
$300,000
Award Maximum
Funding opportunity number:
RFA-CA-25-004
Cost sharing or matching requirement:
No
Funding instrument type:
Grant
Opportunity Category:
Discretionary
Opportunity Category Explanation:
--
Category of Funding Activity:
Education
Health
Category Explanation:
--
History
Version:
1
Posted date:
December 16, 2024
Archive date:
November 8, 2025
