Hermes
Agency: DARPA - Biological Technologies Office
Assistance Listings
- 12.910 -- Research and Technology Development
Archived opportunityLast Updated: May 13, 2026
View version history on Grants.gov
Description
The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals to develop systemic drug delivery platforms for medical countermeasures (MCMs). The Hermes program is explicitly seeking transformative approaches enabling the development of delivery platforms with systemic biodistribution, exceptional endosomal escape efficiency, and minimal toxicity. Successful proposals will include a detailed description of the proposed delivery platform including 1) screening pipeline, 2) reporter systems for monitoring biodistribution and expression in animal models, 3) methods to monitor...
immunogenicity/toxicity, and 4) chosen therapeutic cargo and justification. Systemic delivery platforms developed under the Hermes effort will be transferred to U.S. Government stakeholders for further development.
Eligibility
Eligible applicants
Miscellaneous
- Other
Additional information
All responsible sources capable of satisfying the Government's needs may submit a proposal that shall be considered by DARPA. See the Eligibility Information section of the BAA for more information.
Grantor contact information
Description
Dr. Shannon Greene
HermesBAA@darpa.mil
Documents
| File name | Description | Last updated |
|---|---|---|
| HR001124S0025-Amendment-01.pdf | HR001124S0025-Amendment-01.pdf | May 14, 2024 07:01 PM UTC |
| HERMES_BAA_Attachment_A_Abstract_Summary_Side_Template.pptx | Updated attachment A | Apr 19, 2024 05:41 PM UTC |
| HERMES_BAA_Attachment_F_DARPAStandardCostProposalSpreadsheetSingleTA.xlsx | Updated attachment F | Apr 19, 2024 05:41 PM UTC |
| HR001124S0025.pdf | HR001124S0025.pdf | Apr 19, 2024 05:41 PM UTC |
| HERMES_BAA_Attachment_B_Abstract_Instructions_and_Template.docx | Updated attachment B | Apr 19, 2024 05:41 PM UTC |
| HERMES_BAA_Attachment_D_Proposal_Instructions_and_Volume_I_Template__Technical_and_Management.docx | Updated attachment D | Apr 19, 2024 05:41 PM UTC |
| HERMES_BAA_Attachment_E_Proposal_Instructions_and_Volume_II_Template__Cost.docx | updated attachment E | Apr 19, 2024 05:41 PM UTC |
| HERMES_BAA_Attachment_C_Proposal_Summary_Slide_Template.pptx | updated attachment C | Apr 19, 2024 05:41 PM UTC |
Link to additional information
Archived: July 4, 2024
Award
$--
Program Funding
--
Expected awards
$--
Award Minimum
$--
Award Maximum
Funding opportunity number:
HR001124S0025
Cost sharing or matching requirement:
No
Funding instrument type:
Other
Cooperative agreement
Procurement contract
Grant
Opportunity Category:
Discretionary
Opportunity Category Explanation:
--
Category of Funding Activity:
Science technology and other research and development
Category Explanation:
--
History
Version:
2
Posted date:
April 19, 2024
Archive date:
July 4, 2024
