US Platform to Measure Effectiveness of Seasonal Influenza, COVID-19 and other Respiratory Virus Vaccines for the Prevention of Acute Illness in Ambulatory Settings

Agency: Centers for Disease Control and Prevention - ERA

93.185 -- Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects
93.083 -- Prevention of Disease, Disability, and Death through Immunization and Control of Respiratory and Related Diseases

Archived opportunityLast Updated: May 13, 2026

Description

Influenza and other respiratory illnesses, including COVID-19, are important causes of morbidity, mortality, and healthcare burden across all age groups. For influenza and novel vaccines, such as for COVID-19, estimates of vaccine effectiveness in preventing illness and associated complications are needed in order to evaluate the protection provided by nationwide vaccination programs. The goal of this notice of funding opportunity is to support a network of US institutions that can: a) conduct systematic testing for laboratory-confirmed disease due to influenza, SARS-CoV-2 and other respiratory...

virus infections, b) obtain reliable vaccination information for enrolled patients and c) provide accurate estimates of the effectiveness of vaccines against respiratory viruses, including influenza and SARS-CoV-2 and other respiratory viruses, to prevent medically attended influenza-associated illness in the population for whom vaccination is recommended.

Eligibility

Eligible applicants

Government

Federally recognized Native American tribal governments
County governments
City or township governments
Special district governments
State governments
Public and Indian housing authorities

Nonprofit

Nonprofits non-higher education without 501(c)(3)
Nonprofits non-higher education with 501(c)(3)
Other Native American tribal organizations

Education

Independent school districts
Public and state institutions of higher education
Private institutions of higher education

Miscellaneous

Other

Business

For-profit organizations other than small businesses
Small businesses

Additional information

N/A

Grantor contact information

Description

Amy Yang AYang@cdc.gov

Email

AYang@cdc.gov

Documents

File name	Description	Last updated
Foa_Content_of_RFA-IP-22-004.pdf	Foa_Content_of_RFA-IP-22-004.pdf	Mar 8, 2022 09:36 PM UTC
Foa_Content_of_RFA-IP-22-004_Amendment.pdf	Foa_Content_of_RFA-IP-22-004 Amendment.pdf	Mar 17, 2022 04:55 PM UTC

Link to additional information

Archived: June 8, 2022

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$107,500,000

Program Funding

Expected awards

$2,000,000

Award Minimum

$9,100,000

Award Maximum

Funding opportunity number:

RFA-IP-22-004

Cost sharing or matching requirement:

Funding instrument type:

Cooperative agreement

Opportunity Category:

Discretionary

Opportunity Category Explanation:

Category of Funding Activity:

Health

Category Explanation:

History

Version:

Posted date:

March 8, 2022

Archive date:

June 8, 2022