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Commercial Domestic Production of Moly-99 without the Use of Highly Enriched Uranium

Agency: NNSA

Assistance Listings
  • 81.009 -- Molybdenum-99 Program

Archived opportunityLast Updated: May 13, 2026

View version history on Grants.gov

The U.S. Department of Energy National Nuclear Security Administration’s (DOE/NNSA) Office of Material Management and Minimization (NA-23) is soliciting applications from commercial entities that will result in the award of one or more Cooperative Agreements to achieve commercial-scale production of the medical isotope, molybdenum-99, hereafter referred to as Mo-99, without the use of highly enriched uranium (HEU) in the United States. This FOA closes and applications are due September 30, 2020 by 11:59 p.m. EST. Please be aware that technical difficulties are always possible when submitting applications electronically, therefore, ensure enough time is allotted for submission to DOE/NNSA. DOE/NNSA will not consider any applications that are received after the application deadline. This includes applications which are received by DOE/NNSA late as a result of technical difficulties. Therefore, applicants are strongly encouraged to submit their applications well in advance of the application deadline.


The applicant’s proposal will be evaluated, in accordance with Section V of this FOA, to measure the degree to which the applicant’s approach will enable their project to produce and sell at least 1,500 6-day Ci/week of Mo-99 without the use of HEU to the U.S. market on or before December 31, 2023.The applicant must also possess the ability and plans to increase the production of Mo-99 to 3,000 6-day Ci/week. This FOA is not intended to support Research and Development (R&D) projects, and the applicant must clearly demonstrate their ability to commercially produce Mo-99 on or before December 31, 2023.


Awards under this FOA are subject to the availability of funds. Acceptance of an application for evaluation does not obligate DOE/NNSA to make an award. DOE/NNSA reserves the right to fund, in whole or in part, any, all, or none of the applications submitted in response to this FOA. DOE/NNSA also reserves the right to award with or without discussions with applicants.


Cooperative Agreements (CA) will be awarded on a 50%/50% Federal/non-Federal cost-sharing basis whereby the U.S. Government can provide up to $35 million for one or more awards. The recipient will be required to match the U.S. Government contribution and must demonstrate funds are available by providing investor letters of commitment with each application. DOE/NNSA reserves the right to establish the maximum ceiling amount pre and post award. The funding will begin at or near the time of award and continue over the life of the stated project period of the CA, which will be for a period of three years from the date of award.


Interested parties should carefully read the instructions for preparation of the application. If material or forms are omitted, the application is received after the closing date, or for any other reason an applicant does not provide a complete application by the closing date, the application will be rejected and will not be evaluated. DOE/NNSA does not intend to reissue this FOA. Therefore, any qualified candidates are encouraged to submit applications at this time.


In the event that a Cooperative Agreement is terminated for any reason, following the award date, DOE/NNSA reserves the right to consider other qualified candidates from this FOA for evaluation and consideration.


Cost Sharing:

A 50%/50% cost-sharing arrangement between the U.S. Government and each recipient of federal funding in support of commercial projects, such as the Cooperative Agreements contemplated under this FOA, is required by the Energy Policy Act of 2005, Section 988, codified at 42 U.S.C. § 16352. This statute also prohibits DOE/NNSA from counting “proceeds from the prospective sale of an asset of an activity,” such as the commercial sale of Mo-99 products, towards a recipient’s required cost-sharing contribution. Therefore, applications that propose less than a 50 percent cost-share contribution from non-federal sponsors, or that propose the use of proceeds from the sale of assets generated under the activities of a Cooperative Agreement, shall not be considered for award. Repayment of the Federal share of the cost-shared activity shall not be required as a condition of the award. Investor Letters of Commitment will be required as part of the application.




Eligibility

Eligible applicants

Business

  • For-profit organizations other than small businesses

Additional information

Only domestic entities with mature technologies to achieve commercial-scale production of Mo-99 without the use of highly enriched uranium (HEU) in a facility or using facilities located in the United States in accordance with the goals of this FOA may submit applications. The following types of entities are eligible to apply: small or large public, quasi-public The following types of entities are eligible to apply: small or large public, quasi-public, or private for-profit or non-profit organizations (such as commercial companies, research institutes, or hospitals). National laboratories, all DOE/NNSA Management and Operating contractors, Universities and Institutions of Higher Education, and other Federally Funded Research and Development Centers are not eligible to apply for an award under the FOA. However, applicants may include Institutions of Higher Education in their teaming arrangements as long as they are not team leaders and are not performing a significant portion of the work subject to the conditions in Section I.J of this FOA. The contractor effort, in aggregate, shall not exceed 50% of the total estimated cost of the project, including the applicant’s and the contractor’s portions of the effort. The participation of the national laboratories must be limited to research and development work that they are uniquely qualified to provide, and the financial arrangement is with the applicant directly.

Grantor contact information

Description

Delmeria Pacheco Grants Management Officer

Email

Submit all questions thru Fedconnect.net

delmeria.pacheco@nnsa.doe.gov

Documents

File nameDescriptionLast updated
Attach_2_NEPA_-_Copy.docx
FA NEPA Checklist
Jul 31, 2020 01:34 PM UTC
Assurances_for_Construction_SF-424D.pdf
SF-424D Assurances for Construction Programs
Jul 31, 2020 02:49 PM UTC
Attch_3_Environmental_Questionnaire_Guidance.docx
FA NEPA Questionnaire Guidance
Jul 31, 2020 01:36 PM UTC
FOA-0002303.docx
Funding Opportunity Announcement DE-FOA-0002303
Jul 31, 2020 01:42 PM UTC
Attch_1-Sample_Budget_Spreadsheet_7Jul18.xlsx
Sample Excel Budget Spreadsheet
Jul 31, 2020 01:31 PM UTC

Link to additional information

Fedconnect.net

Archived: October 30, 2020

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$35,000,000

Program Funding

10

Expected awards

$15,000,000

Award Minimum

$35,000,000

Award Maximum

Funding opportunity number:

DE-FOA-0002303

Cost sharing or matching requirement:

Yes

Funding instrument type:

Cooperative agreement

Opportunity Category:

Discretionary

Opportunity Category Explanation:

--

Category of Funding Activity:

Energy

Category Explanation:

--

History

Version:

1

Posted date:

July 31, 2020

Archive date:

October 30, 2020

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