ADVANCING TOXICOKINETICS FOR EFFICIENT AND ROBUST CHEMICAL EVALUATIONS
Agency: Environmental Protection Agency
Assistance Listings
- 66.509 -- Science To Achieve Results (STAR) Research Program
Archived opportunityLast Updated: May 13, 2026
View version history on Grants.gov
Description
The U.S. Environmental Protection Agency (EPA), as part of its Science to Achieve Results (STAR) program, is seeking applications proposing to advance the development of chemical toxicokinetic tools and approaches for broader applicability during chemical evaluations, with an emphasis on their application within new approach methodology (NAM) frameworks. Toxicokinetics describes the absorption, distribution, metabolism, and excretion of chemicals and their metabolites by the body, and as such provides a framework for extrapolating in vivo doses of concern from in vitro-derived concentrations that cause perturbations at the cellular or molecular level. The incorporation of new methods, tools and approaches can simultaneously improve predictivity, reduce uncertainty and build confidence in the successful application of such extrapolations.
Eligibility
Eligible applicants
Miscellaneous
- Other
Additional information
See Section III of the solicitation for eligibility information.
Grantor contact information
Description
Technical Contact: Barbara Klieforth; phone: 202-564-7223; email: klieforth.barbara@epa.gov
Eligibility Contact: Ron Josephson; phone: 202-564-7823; email: josephson.ron@epa.gov
Electronic Submissions Contact: Debra M. Jones; phone: 202-564-7839; email: jones.debram@epa.gov
jones.debram@epa.gov
Documents
| File name | Description | Last updated |
|---|---|---|
| httk_rfa_061719_ioaa_edits_ncer_ddd_data_highlight_mrh_5_1.pdf | announcement | Aug 16, 2019 02:23 PM UTC |
Link to additional information
Avancing Toxicokinetics for Efficient and Robust Chemical Evaluations
Archived: October 24, 2019
Award
$4,000,000
Program Funding
5
Expected awards
$--
Award Minimum
$800,000
Award Maximum
Funding opportunity number:
EPA-G2019-STAR-D1
Cost sharing or matching requirement:
No
Funding instrument type:
Grant
Opportunity Category:
Discretionary
Opportunity Category Explanation:
--
Category of Funding Activity:
Environment
Category Explanation:
--
History
Version:
2
Posted date:
July 25, 2019
Archive date:
October 24, 2019
