CDC/ATSDR is inviting research proposals to study risk factors for Amyotrophic Lateral Sclerosis (ALS). Studies on military service, contact sports, traumatic brain injury, neuroinflammation, and infections agents and exposures are encouraged. Funding will be for four funding options: Option A - Support research with strong existing evidence such as studies on known environmental or genetic risk factors, research that improves past studies with better data, or investigations linking risk factors to ALS diagnosis and treatment; Option B - Support new and exploratory research on ALS risk factors such as studies on risk factors with little existing evidence or research using innovative methods; Option C - Understand ALS risk in affected populations, such as studies involving military veterans or investigations of ALS risk factors impacting this population; Option D - Analyze biological samples from the Guamanian ALS cluster such as investigation of disease mechanisms and environmental factors, exposure routes, genetic studies and biomarkers and how this could lead to mitigation therapeutics, diagnostics or prevention. 

Miscellaneous

• Other
• Unrestricted

Government

• Federally recognized Native American tribal governments
• County governments
• City or township governments
• Special district governments
• Public and Indian housing authorities
• State governments

Education

• Public and state institutions of higher education
• Independent school districts
• Private institutions of higher education

Nonprofit

• Other Native American tribal organizations
• Nonprofits non-higher education with 501(c)(3)
• Nonprofits non-higher education without 501(c)(3)