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Controlling and Preventing STIs in US Health Departments (CAP-STIs)

Agency: Centers for Disease Control - NCHHSTP

Assistance Listings: 93.977 -- Sexually Transmitted Diseases (STD) Prevention and Control Grants

Last Updated: May 13, 2026

Description

CDC is funding programs that track, prevent, and control sexually transmitted infections (STI) in state, district, territorial, and city or county health departments.

The purpose of this NOFO is to track, prevent, and control three common STIs: syphilis, gonorrhea, and chlamydia.

The NOFO supports the goals of the Sexually Transmitted Infections National Strategic Plan 2021-2025:

  • Prevent new STIs.
  • Improve the health of people by reducing adverse outcomes of STIs.
  • Implement STI prevention technology and innovations more quickly.
  • Reduce the impact of STIs in areas or populations disproportionately impacted by STIs.
  • Achieve integrated, coordinated efforts that address the STI epidemic.

Local surveillance data will determine the priority populations for this NOFO. Each program should focus on populations that are disproportionately impacted by STI transmission. 

To be successful with this NOFO, you will need to collaborate with partners to address interconnected comorbidities and sexual health.

Eligibility

Eligible applicants

Miscellaneous

  • Unrestricted
  • Other

Government

  • City or township governments
  • County governments
  • State governments
  • Special district governments

Additional information

All fifty (50) states, the District of Columbia, the US Virgin Islands and Puerto Rico are eligible to apply. To ensure implementation of STI control and prevention nationwide, CDC intends to fund all fifty states, the District of Columbia, the US Virgin Islands and Puerto Rico, non-competitively, according to a funding formula based on the respective jurisdiction"s population & morbidity of three reportable STIs (chlamydia, gonorrhea and primary & secondary syphilis).Section 318(c) of the Public Health Services Act, 42 USC 247c(c), provides that the Secretary of HHS may provide funding to "States and, in consultation with the State health authority, to political subdivisions of States..." to conduct STI prevention & control projects. This language allows CDC to fund cities in addition to their respective states. Under the previous STI prevention & control funding opportunity PS19-1901 (& prior to that, PS14-1402), CDC funded the following cities based upon population, STI morbidity & organizational capacity: New York City, Philadelphia, Baltimore, Chicago, Los Angeles & San Francisco.To maximize the efficiency of program delivery, CDC may again fund a limited number of cities under this award. Funding for cities will be awarded competitively, based on the same criteria shown above for the state formula: population, STI morbidity, as well as organizational capacity. Directly funded cities must have a demonstrated capacity to report chlamydia, gonorrhea and syphilis surveillance data to CDC; an agreement with their parent state to apply separately for NOFO funding & to coordinate/collaborate appropriately following any funding; & data showing that the surrounding metropolitan statistical area (MSA) reported 2024 data showing:> or = to 500 cases of syphilis aged 15-44 reported in 2024 > or = 7500 cases of gonorrhea aged 15-44 reported in 2024 > or = to 15,000 cases of chlamydia aged 15-44 reported in 2024 > or = to 4 million residents estimated in 2024 Cities that apply for funding must submit their 2024 surveillance summary demonstrating the number of required cases & residents, a joint statement of collaboration/coordination with their respective state, or a letter indicating the city has notified the state of its application for funding of this award. In the event that cities do not compete successfully for the funding, all funds will be provided to the state, which will be responsible for distributing funds to its constituent cities as appropriate.

Grantor contact information

Description

Puja Seth (404) 639-6334

Email

idj5@cdc.gov

idj5@cdc.gov

Documents

No documents are currently available.

Link to additional information

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Forecasted

Estimated Post Date:

June 30, 2026

Estimated Application Due Date:

August 29, 2026

Estimated Due Date Description:

Not available

Estimated Award Date:

February 1, 2027

Estimated Project Start Date:

February 1, 2027

Fiscal Year:

2027

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$500,000,000

Program Funding

59

Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

CDC-RFA-PS-27-0008

Cost sharing or matching requirement:

No

Funding instrument type:

Cooperative agreement

Opportunity Category:

Discretionary

Opportunity Category Explanation:

--

Category of Funding Activity:

Health

Category Explanation:

--

History

Version:

1

Forecast posted date:

May 11, 2026

Archive date:

September 28, 2026

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