This Notice of Funding Opportunity (NOFO) announcement invites applications for NIDDK Multi-Purpose Resource-Related Research, Multi-Component Centers Cooperative Agreement (U2C - Clinical Trial Not Allowed).  To help increase rigor, reproducibility and cost efficiencies, U2C centers offer highly specialized cores that provide a range of topic focused services including but not limited to hands-on technical services, consulting, research/data coordination, or other research support services provided by nationally recognized experts.  In contrast to other types of Core Centers, the U2C services should be largely provided to clients located at another institution where the needed service or expertise is not available.  Provided services enable high impact research within NIDDK’s research mission including but not limited to integrative physiology, metabolic phenotyping, nutrition, community engagement, communications, and/or data and research coordination.  The disease focus should similarly be within NIDDK’s mission, such as obesity and diabetes. The clients for these services can be a consortia, research partners or individual investigators and should offer experiential training in at least one of the provided services. Applications to this NOFO can propose optional opportunities and/or a pilot and feasibility grant program depending on the needs of the program.

Government

• State governments
• Federally recognized Native American tribal governments
• Public and Indian housing authorities
• County governments
• City or township governments
• Special district governments

Business

• Small businesses
• For-profit organizations other than small businesses

Education

• Private institutions of higher education
• Independent school districts
• Public and state institutions of higher education

Nonprofit

• Other Native American tribal organizations
• Nonprofits non-higher education with 501(c)(3)
• Nonprofits non-higher education without 501(c)(3)

Miscellaneous

• Other