Understanding and Promoting Resources and Opportunities for People with Autism and Fragile X and their Families Across the Lifespan
Agency: Centers for Disease Control - NCBDDD
Assistance Listings: 93.073 -- Birth Defects and Developmental Disabilities - Prevention and Surveillance
Last Updated: May 15, 2026
Description
The goal of this NOFO is to gather unique information not collected by other federal programs to gain a better understanding of the resources (e.g., services, supports) and opportunities (e.g., education, employment, housing, social participation) needed to reduce morbidity, mortality, and economic impacts and improve other long-term outcomes for people with autism or Fragile X Syndrome (FXS) across the lifespan. CDC proposes to implement three components in this NOFO.Component A: Survey to Promote Resources and Opportunities for aUtistic Teens and young adults (SPROUT) will utilize cohorts from...
the Study to Explore Early Development (SEED) Phases 1-3 (collected from 2007-2020), which were case-control studies of autism in children 2-5 years of age. Participants will range from about 10-25 years of age when this NOFO is awarded. SPROUT will be comprised of caregiver and self-report surveys intended to offer unique information on (1) service and support needs and the impact of co-occurring conditions on autistic people and their families and (2) the educational, transitional, social, and/or vocational needs and experiences of autistic adolescents and young adults. Information from these surveys will be used to improve the health and wellbeing of autistic people and their families. These activities are intended to provide data to inform ways to lessen individual, familial, and societal costs associated with autism, reduce morbidity and mortality, and improve health and well-being.Component B: Focus on Advancing Support and Transition with the Fragile X Online Registry With Accessible Research Database (FAST FORWARD) awardees will employ clinic-based enrollment of eligible participants with a recruitment goal of at least 200 eligible persons with FXS per clinic. Similar to SPROUT, awardees will collect data on (1) timing of and barriers to diagnosis, (2) service and support needs and the impact of co-occurring conditions on people with FXS and their families and (3) the educational, transitional, social, and/or vocational needs and experiences of people with FXS and their families. Awardees will participate in project meetings, recruit participants, collect data, record data in a centralized platform, and produce quality public health products. These activities are intended to provide data to inform ways to lessen individual, familial, and societal costs associated with FXS, reduce morbidity and mortality, and improve health and well-being. Component C: The purpose of this component is to disseminate quality public health products that can improve the health and wellbeing of people with FXS and their families. The awardee will participate in project meetings, develop materials, and disseminate materials to relevant audiences to strengthen the capacity among healthcare providers to appropriately support patients with FXS on a national level.
Eligibility
Eligible applicants
Education
- Private institutions of higher education
- Independent school districts
- Public and state institutions of higher education
Nonprofit
- Other Native American tribal organizations
- Nonprofits non-higher education without 501(c)(3)
- Nonprofits non-higher education with 501(c)(3)
Government
- Federally recognized Native American tribal governments
- Special district governments
- Public and Indian housing authorities
- City or township governments
- State governments
- County governments
Miscellaneous
- Unrestricted
Business
- For-profit organizations other than small businesses
- Small businesses
Additional information
Component A (Autism Data Collection and Dissemination): Applicants must have documented access to individual contact and eligibility data from participants in the Study to Explore Early Development (SEED) phases 1, 2, and/or 3 for all cohorts they propose to include in their recruitment pool to ensure successful completion of the data collection outlined in Component A of the NOFO. Therefore, applicants must either: 1) be the original entities that collected the original SEED data on children 2-5 years of age and their parents/caregivers, and therefore have the information needed to reach these individuals for the Survey to Promote Resources and Opportunities for aUtistic Teens and young adults (SPROUT); OR 2) have established collaborative agreements to work with the entities that originally collected contact information from SEED participants (i.e., former SEED recipients) so that they can reach the SEED participants for the data collection as outlined in Component A of the NOFO.Component B (Fragile X Data Collection): Applicants must provide evidence of access to clinic-based samples of children, adolescents, and adults (ages 0-40 years) with fragile X syndrome (FXS) full mutation diagnosis and demonstrate their ability and capacity to collect data on a minimum of 200 unique individuals in this population as outlined in Component B of the NOFO.Component C (Fragile X Data Dissemination): Applicants must demonstrate their ability and capacity to identify and reach populations of people with FXS and their families and communities, as well as healthcare providers, particularly those treating FXS patients, across the United States. Applicants must also demonstrate their ability to generate new communication and continually identify and update resources for the target populations, and well as quantify metrics of impact. Their history of outreach to these populations should include (but may not be limited to) evidence-based educational information, resources, and support.
Grantor contact information
Description
Seema Gupta
cvk9@cdc.gov
cvk9@cdc.gov
Documents
| File name | Description | Last updated |
|---|---|---|
| cdc-rfa-dd-26-0025_ForPublication.pdf | cdc-rfa-dd-26-0025_ForPublication.pdf | May 15, 2026 07:09 PM UTC |
Link to additional information
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Closing: June 15, 2026
Electronically submitted applications must be submitted no later than 11:59 pm ET on the listed application due date.
Award
$18,000,000
Program Funding
11
Expected awards
$--
Award Minimum
$--
Award Maximum
Funding opportunity number:
CDC-RFA-DD-26-0025
Cost sharing or matching requirement:
No
Funding instrument type:
Cooperative agreement
Opportunity Category:
Discretionary
Opportunity Category Explanation:
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Category of Funding Activity:
Health
Category Explanation:
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History
Version:
1
Posted date:
May 15, 2026
Archive date:
October 1, 2026
