Opportunity Listing - Device Based Treatments for Substance Use Disorders (UG3/UH3 Clinical Trial Optional)

Device Based Treatments for Substance Use Disorders (UG3/UH3 Clinical Trial Optional)

Agency: National Institutes of Health

Assistance Listings: 93.279 -- Drug Abuse and Addiction Research Programs

Last Updated: November 24, 2025

Description

The purpose of this Funding Opportunity Announcement (FOA) is to accelerate the development of devices to treat Substance Use Disorders (SUDs). The continuing advances in technologies offer unprecedented opportunities to develop neuromodulatory or neurophysiological devices that are safe and effective SUD treatments. The objective is to move devices to their next step in the FDA approval process, with the ultimate goal of generating new, FDA approved device-based treatments for SUDs.

Eligibility

Eligible applicants

Government

State governments
County governments
Public and Indian housing authorities
Federally recognized Native American tribal governments
Special district governments
City or township governments

Nonprofit

Other Native American tribal organizations
Nonprofits non-higher education with 501(c)(3)
Nonprofits non-higher education without 501(c)(3)

Business

For-profit organizations other than small businesses
Small businesses

Education

Private institutions of higher education
Independent school districts
Public and state institutions of higher education

Miscellaneous

Other

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Documents

File name	Description	Last updated
PAR-25-023-Full-Announcement.html	PAR-25-023 Full Announcement Text	Oct 31, 2024 08:08 PM UTC

Link to additional information

https://grants.nih.gov/grants/guide/pa-files/PAR-25-023.html

Closed: November 24, 2025

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$--

Program Funding

Expected awards

$--

Award Minimum

$500,000

Award Maximum

Funding opportunity number:

PAR-25-023

Cost sharing or matching requirement:

Funding instrument type:

Cooperative agreement

Opportunity Category:

Discretionary

Opportunity Category Explanation:

Category of Funding Activity:

Education

Health

Category Explanation:

History

Version:

Posted date:

July 12, 2024

Archive date:

December 24, 2025