to nurture, grow and recognize the national CIP[1] workforce that is essential forcreating, utilizing andsupportingadvanced CI to enable and potentially transform fundamental science and engineering (S&E) research and education and contribute to the Nation's overall economic competitiveness and security. Together, the principal investigators (PIs), technology platforms, tools, and expert CIP workforce supported by this solicitation operate as an interdependent ecosystem wherein S&E research and education thrive. This solicitation willsupport NSF’s advanced CI ecosystem with a scalable, agile, and sustainable network of CIPs that can ensurebroad adoptionof advanced CI resources and expert services including platforms, tools, methods, software, data, and networks for research communities, to catalyze major research advances, and to enhance researchers' abilities to lead the development of new CI. The SCIPE program is led by the Office of Advanced Cyberinfrastructure (OAC) in the Directorate for Computer and Information Science and Engineering (CISE) and has participation from other NSF directorates/divisions, as described in Section II. Program Description,Programmatic Areas of Interest. Not all directorates/divisions are participating at the same level, and some have specific research and education priorities. The appropriate contact for the SCIPE program in any directorate/division is the Cognizant Program Officer (PO) for the respective directorate/division/office/program listed below. All projects are expected to clearly articulate how they address essential community needs, will provide resources that will be widely available to and usable by the research community.Prospective PIs arestrongly encouragedto contact the Cognizant Program Officers in CISE/OACandin the participating directorate/division relevant to the proposal to ascertain whether the focus and budget of their proposed activities are appropriate for this solicitation.Such consultations should be completed at least one month before the submission deadline. PIs should include the names of the Cognizant Program Officers consulted in a Single Copy Document as described in Section V.A. Proposal Preparation Instructions. The intent of the SCIPE program is to encourage collaboration between CI and S&E domain disciplines. (For this purpose, units of CISE other than OAC are considered domain disciplines.) To ensure relevance to community needs and to facilitate adoption, those proposals of interest to one or more domain divisionsmustinclude at least one PI/co-PI with expertise relevant to the targeted research discipline. All proposals shall include at least one PI/co-PI with expertise pertinent to OAC. Prospective PIs contemplating submissions that primarily target communities relevant to directorates/divisions that are not participating in this solicitation are directed to explore instead the education and workforce development programs of the respective directorates/divisions. [1] ⁹CI Professionals refers to the community of individuals who provide a broad spectrum of skills and expertise to the scientific and engineering research enterprise by inventing, developing, deploying and/or supporting research CI and CI users. Examples of CI Professionals include CI system administrators, CI research support staff, CI research software engineers, data curators, and CI facilitators, and may also include computational research scientists and engineers who are not in traditional academic paths.See:Transforming Science Through Cyberinfrastructure: NSF’s Blueprint forCyberinfrastructure Learning and Workforce Development,https://www.nsf.gov/cise/oac/vision/blueprint-2019/CI-LWD.pdf.