BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61 Basic Experimental Studies with Humans Required)
Agency: National Institutes of Health
Assistance Listings: 93.173 -- Research Related to Deafness and Communication Disorders
Description
The National Institute on Deafness and Other Communication Disorders (NIDCD), National Eye Institute (NEI), National Institute on Aging (NIA), National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Institute of Biomedical Imaging and Bioengineering (NIBIB), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institute on Drug Abuse (NIDA), National Institute of Mental Health (NIMH), National Institute of Neurological Disorders and Stroke (NINDS), and National Center for Complementary and Integrative Health (NCCIH), intend to reissue RFA-DC-24-001 a Notice of Funding Opportunity (NOFO) to solicit applications. Research on invasive surgical procedures in humans offer the unique opportunity to intracranially record and stimulate neuronal activity within precisely localized brain structures, enabling high-impact human neuroscience investigations. This NOFO seeks exploratory research projects, from newly formed or established multi-disciplinary teams, to understand how dynamic activity of single cells and ensembles of neurons in spatially organized networks gives rise to the internal states we experience as sensations, perceptions, emotions, thoughts, and memories, and to observable motor and social behaviors. The research should be proposed as exploratory research and planning activities to establish feasibility and early-stage development that, if successful, would support, enable, and/or lay the groundwork for a potential, subsequent research project grant applications using invasive neural recording and stimulation technologies in the human brain. Projects should maximize opportunities to conduct innovative in vivo human neuroscience research made available by direct access to the brain from invasive surgical procedures. Projects should employ approaches guided by specified theoretical constructs and by quantitative, mechanistic models where appropriate.
...Recipients will join a consortium working group, coordinated by the NIH, to identify consensus standards of practice, including neuroethical considerations, to collect and provide data for ancillary studies, and to aggregate and standardize data for dissemination among the wider scientific community.
Eligibility
Eligible applicants
Government
- Public and Indian housing authorities
- County governments
- Federally recognized Native American tribal governments
- State governments
Business
- For-profit organizations other than small businesses
- Small businesses
Education
- Public and state institutions of higher education
- Independent school districts
- Private institutions of higher education
Nonprofit
- Other Native American tribal organizations
- Nonprofits non-higher education with 501(c)(3)
Additional information
Grantor contact information
Description
BRAINeROH@ninds.nih.gov
Documents
No documents are currently available here
Link to additional information
--
Forecasted
Estimated Post Date:
August 15, 2025
Estimated Application Due Date:
September 15, 2025
Estimated Due Date Description:
Not available
Estimated Award Date:
June 29, 2026
Estimated Project Start Date:
July 29, 2026
Fiscal Year:
2026
Award
$--
Program Funding
--
Expected awards
$--
Award Minimum
$--
Award Maximum
Funding opportunity number:
NOT-DC-25-037
Cost sharing or matching requirement:
Funding instrument type:
Grant
Opportunity Category:
Discretionary
Opportunity Category Explanation:
Category of Funding Activity:
Health
Category Explanation:
History
Version:
1
Forecast posted date:
June 9, 2025
Archive date:
--