NIH Directors Pioneer Award Program (DP1 Clinical Trial Optional)
Agency: National Institutes of Health
Assistance Listings: 93.310 -- Trans-NIH Research Support
Last Updated: June 13, 2025
Description
The NIH Directors Pioneer Award Program supports individual scientists of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the mission of NIH. To support innovative and novel research across the vast NIH mission, individuals from diverse backgrounds (including those from underrepresented groups; see Notice of NIHs Interest in Diversity) and from the full spectrum of eligible institutions in all geographic locations are encouraged to apply to this Notice of Funding Opportunity. Applications...
in all topics relevant to the broad mission of NIH are welcome, including, but not limited to, topics in the behavioral, social, biomedical, applied, and formal sciences and topics that may involve basic, translational, or clinical research. The NIH Directors Pioneer Award is a component of the High-Risk, High-Reward Research (HRHR) Program of the NIH Common Fund.
Eligibility
Eligible applicants
Government
- State governments
- Public and Indian housing authorities
- County governments
- Special district governments
- City or township governments
- Federally recognized Native American tribal governments
Education
- Private institutions of higher education
- Independent school districts
- Public and state institutions of higher education
Nonprofit
- Nonprofits non-higher education without 501(c)(3)
- Other Native American tribal organizations
- Nonprofits non-higher education with 501(c)(3)
Miscellaneous
- Other
Business
- For-profit organizations other than small businesses
- Small businesses
Additional information
Other Eligible Applicants include the following:
Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.
Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Grantor contact information
Description
NIH Grants Information
grantsinfo@nih.gov
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
Documents
| File name | Description | Last updated |
|---|---|---|
| RFA-RM-25-001-Full-Announcement.html | RFA-RM-25-001 Full Announcement Text | Jun 13, 2025 03:47 PM UTC |
Link to additional information
https://grants.nih.gov/grants/guide/rfa-files/RFA-RM-25-001.html
Closing: September 9, 2025
Award
$--
Program Funding
--
Expected awards
$--
Award Floor
$700,000
Award Ceiling
Funding opportunity number:
RFA-RM-25-001
Cost sharing or matching requirement:
No
Funding instrument type:
Grant
Opportunity Category:
Discretionary
Opportunity Category Explanation:
--
Category of Funding Activity:
Health
Category Explanation:
--
History
Version:
1
Posted date:
June 12, 2025
Archive date:
October 15, 2025
