The purpose of this Notice of Funding Opportunity (NOFO) is to fund clinical trials of products evaluating efficacy and/or safety in support of a new indication or change in labeling to address unmet needs in rare neurodegenerative diseases for children and adults. Through the support of collaborative, efficient, and/or innovative clinical trials, FDA expects to increase the number of approved treatments for rare neurodegenerative diseases and exert a broad and positive impact on rare disease drug development.

Business

• For-profit organizations other than small businesses
• Small businesses

Miscellaneous

• Unrestricted

Education

• Public and state institutions of higher education
• Private institutions of higher education
• Independent school districts

Government

• Federally recognized Native American tribal governments
• Public and Indian housing authorities
• State governments
• City or township governments
• Special district governments
• County governments

Nonprofit

• Other Native American tribal organizations
• Nonprofits non-higher education without 501(c)(3)
• Nonprofits non-higher education with 501(c)(3)